One early study of orgasms suggests that the subjective experience of orgasm is very similar between men and women. Despite having different anatomies, men and women seem to be hard-wired to experience sexual pleasure in the same way. But does this translate to a similarity in the brain?
(…) But when Holstege tested women, he found something surprising. Much more so than men’s brains, female brains go mysteriously silent during orgasm. In particular, the left lateral orbitofronal cortex and the dorsomedial prefrontal cortex, areas involved in self-control and social judgment, respectively, are deactivated. Brain activity also fell in the amygdala, suggesting a similar, albeit more drastic, drop in vigilance and emotion as in men. “At the moment of orgasm, women do not have any emotional feelings,” Holstege was quoted as saying."